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K
Katherine A. Fitzgerald
University of Massachusetts Chan Medical School
ORCID https://orcid.org/0000-0003-3175-609X
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Top Publications
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
Nature Immunology
2008
2,984 citations
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Nature Immunology
2010
2,930 citations
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
The Journal of Immunology
2009
2,835 citations
IKKε and TBK1 are essential components of the IRF3 signaling pathway
Nature Immunology
2003
2,672 citations
First author
Corresponding
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Nature Immunology
2008
2,375 citations
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Immunity
2012
2,103 citations
Long non-coding RNAs: definitions, functions, challenges and recommendations
Nature Reviews Molecular Cell Biology
2023
2,071 citations
STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
Immunity
2014
1,776 citations
IFI16 is an innate immune sensor for intracellular DNA
Nature Immunology
2010
1,616 citations
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Nature Immunology
2012
1,359 citations
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
Nature Immunology
2004
1,343 citations
Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
Nature Immunology
2007
1,340 citations
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
Nature Immunology
2010
1,284 citations
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury
Cardiovascular Research
2013
503 citations
Katherine A. Fitzgerald · Scinovex
