article Open AccessTop 1% cited
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Nature Immunology · 2012 · Vol. 13(3) · pp. 255–263
Chong-Shan Shi✉(National Institute of Allergy and Infectious Diseases)Kevin Shenderov(National Institute of Allergy and Infectious Diseases)Ning-Na Huang(National Institutes of Health)Juraj Kabát(National Institute of Allergy and Infectious Diseases)Mones Abu‐Asab(National Eye Institute)Katherine A. Fitzgerald(University of Massachusetts Chan Medical School)Alan Sher(National Institute of Allergy and Infectious Diseases)John H. Kehrl(National Institutes of Health)
Autophagy in Disease and TherapyInflammasome and immune disordersPhagocytosis and Immune RegulationAutophagyInflammasomeSignal transducing adaptor proteinAIM2Cell biologyAutophagosomeUbiquitinCaspase 1InflammationChemistry
MeSH terms
NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsAutophagyCarrier ProteinsCell LineDNA-Binding ProteinsHumansInflammationNuclear ProteinsSignal Transductionral GTP-Binding ProteinsMiceInterleukin-1betaUbiquitinationInflammasomes
Funding
- Tokyo Medical and Dental University
- Takeda Oncology
- National Institute of Allergy and Infectious Diseases
Citations
1,359
FWCI
67.58
field-weighted impact
References
49
Percentile
100%
vs. same field & year
Citations per year
Cited by
Initiation and perpetuation of <scp>NLRP</scp>3 inflammasome activation and assembly
Immunological Reviews · 2015 · 832 citations
Regulation of inflammasome activation
Immunological Reviews · 2015 · 1,061 citations
<scp>PAMP</scp>s and <scp>DAMP</scp>s: signal 0s that spur autophagy and immunity
Immunological Reviews · 2012 · 1,161 citations
Emerging regulation and functions of autophagy
Nature Cell Biology · 2013 · 1,201 citations
Autophagy in infection, inflammation and immunity
Nature reviews. Immunology · 2013 · 1,849 citations
Activation and regulation of the inflammasomes
Nature reviews. Immunology · 2013 · 2,842 citations
Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines
Frontiers in Immunology · 2018 · 1,234 citations
References
Toll-like receptors: critical proteins linking innate and acquired immunity
Nature Immunology · 2001 · 4,755 citations
Mammalian autophagy: core molecular machinery and signaling regulation
Current Opinion in Cell Biology · 2009 · 1,942 citations
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
The EMBO Journal · 2000 · 6,511 citations
p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy
Journal of Biological Chemistry · 2007 · 4,501 citations
Methods in Mammalian Autophagy Research
Cell · 2010 · 4,472 citations
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
Nature reviews. Immunology · 2010 · 1,789 citations
Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages
PLoS Pathogens · 2007 · 530 citations
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
Nature Immunology · 2010 · 1,284 citations
Related articles
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Nature Immunology · 2012 · 1,359 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
