article Open AccessTop 1% cited
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Nature Immunology · 2010 · Vol. 12(3) · pp. 222–230
Kiichi Nakahira✉(Brigham and Women's Hospital)Jeffrey A. Haspel(Harvard University)Vijay Rathinam(University of Massachusetts Chan Medical School)Seon‐Jin Lee(Harvard University)Tamás Dolinay(Harvard University)Hilaire C. Lam(Brigham and Women's Hospital)Joshua A. Englert(Brigham and Women's Hospital)Marlene Rabinovitch(Stanford University)Manuela Cernadas(Harvard University)Hong Pyo Kim(University of Ulsan)Katherine A. Fitzgerald(University of Massachusetts Chan Medical School)Stefan W. Ryter(Harvard University)Augustine M.K. Choi(Brigham and Women's Hospital)
Autophagy in Disease and TherapyInflammasome and immune disordersExtracellular vesicles in diseaseNALP3InflammasomeAutophagyAIM2Cell biologyInnate immune systemCaspase 1CytosolMitochondrionBiology
MeSH terms
NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsAutophagyCarrier ProteinsDNA, MitochondrialFlow CytometryImmunity, InnateCaspase 1MiceInflammasomes
Citations
2,930
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References
Mitochondrial Membrane Permeabilization in Cell Death
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Nature Immunology · 2009 · 1,825 citations
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