review Open AccessTop 1% cited
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease
Cell · 2017 · Vol. 171(2) · pp. 273–285
Brent R. Stockwell✉(Columbia University)José Pedro Friedmann Angeli(Helmholtz Zentrum München)Hülya Bayır(University of Pittsburgh)Ashley I. Bush(University of Melbourne)Marcus Conrad(Helmholtz Zentrum München)Scott J. Dixon(Stanford University)Simone Fulda(German Cancer Research Center)Sergio Gascón(Ludwig-Maximilians-Universität München)Stavroula K. Hatzios(Yale University)Valerian E. Kagan(University of Pittsburgh)Kay NoelXuejun Jiang(Memorial Sloan Kettering Cancer Center)Andreas Linkermann(TU Dresden)Maureen E. Murphy(The Wistar Institute)Michael Overholtzer(Memorial Sloan Kettering Cancer Center)Atsushi Oyagi(Ono Pharmaceutical (United States))Gabriela Carolina Pagnussat(Consejo Nacional de Investigaciones Científicas y Técnicas)Jason Y. Park(Flagship Pioneering (United States))Qitao Ran(The University of Texas Health Science Center at San Antonio)C RosenfeldKonstantin Salnikow(National Cancer Institute)Daolin Tang(Guangzhou Medical University)Frank M. Torti(UConn Health)Suzy V. Torti(UConn Health)Shinya Toyokuni(Nagoya University)K. A. Woerpel(New York University)Donna D. Zhang(University of Arizona)
Ferroptosis and cancer prognosisRNA modifications and cancerCancer, Lipids, and MetabolismBiologyNexus (standard)Programmed cell deathDiseaseCell biologyMetabolismCell metabolismRedoxCellBiochemistry
MeSH terms
AnimalsHumansIronOxidation-ReductionCell DeathApoptosisReactive Oxygen Species
Funding
- Geoffrey Beene Cancer Research Center
- Human Frontier Science Program
- National Natural Science Foundation of China
- National Institutes of Health
- Japan Society for the Promotion of Science
Citations
7,155
FWCI
198.93
field-weighted impact
References
115
Percentile
100%
vs. same field & year
Citations per year
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References
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Molecular Cell · 2015 · 1,981 citations
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cell Death and Differentiation · 2014 · 1,008 citations
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Cell · 2012 · 17,296 citations
Regulation of Ferroptotic Cancer Cell Death by GPX4
Cell · 2014 · 7,213 citations
Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
Cell Metabolism · 2008 · 1,415 citations
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Nature Cell Biology · 2014 · 3,521 citations
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
Cancer Cell · 2003 · 1,396 citations
Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features
Cell Death and Differentiation · 2009 · 625 citations
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