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NRF2 and the Hallmarks of Cancer

Cancer Cell · 2018 · Vol. 34(1) · pp. 21–43
Montserrat Rojo de la VegaEli ChapmanDonna D. Zhang
Genomics, phytochemicals, and oxidative stressGlutathione Transferases and PolymorphismsSynthesis and Biological EvaluationTranscription factorBiologyMetastasisRegulatorCancer cellCancerCancer researchBioinformaticsGeneticsGene

MeSH terms

AnimalsCell MovementCell Transformation, NeoplasticHumansNeoplasm MetastasisNeoplasmsSignal TransductionGene Expression Regulation, NeoplasticDrug Resistance, NeoplasmCell ProliferationNF-E2-Related Factor 2

Funding

  • Action Against Cancer
  • National Institutes of Health
Citations
1,592
FWCI
49.37
field-weighted impact
References
355
Percentile
100%
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Citations per year
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References
The emerging role of Nrf2 in mitochondrial function
Free Radical Biology and Medicine · 2015 · 945 citations
Genomic instability — an evolving hallmark of cancer
Nature Reviews Molecular Cell Biology · 2010 · 2,355 citations
Modulation of oxidative stress as an anticancer strategy
Nature Reviews Drug Discovery · 2013 · 3,495 citations
AP-1 as a regulator of cell life and death
Nature Cell Biology · 2002 · 2,929 citations
Targeting PI3K/mTOR Signaling in Cancer
Frontiers in Oncology · 2014 · 1,030 citations
Regulation of cancer cell metabolism
Nature reviews. Cancer · 2011 · 4,732 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
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