article Open AccessTop 1% cited
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Cell · 2012 · Vol. 149(5) · pp. 1060–1072
Scott J. Dixon✉(Columbia University)Kathryn M. Lemberg(Columbia University)Michael R. Lamprecht(Columbia University)Rachid Skouta(Columbia University)Eleina M. Zaitsev(Columbia University)Caroline E. Gleason(Columbia University)Darpan N. Patel(Columbia University)Andras J. Bauer(Columbia University)Alexandra M. Cantley(Columbia University)Wan Seok Yang(Columbia University)Barclay Morrison(Columbia University)Brent R. Stockwell(Howard Hughes Medical Institute)
Ferroptosis and cancer prognosisTrace Elements in HealthAutophagy in Disease and TherapyBiologyProgrammed cell deathCell biologyApoptosisBiochemistry
MeSH terms
AnimalsCyclohexylaminesFibroblastsHippocampusHumansIronNeoplasmsPhenylenediaminesPiperazinesCell DeathReactive Oxygen SpeciesGlutamic AcidLipid MetabolismRatsIn Vitro Techniques
Funding
- National Science Foundation
- Arnold and Mabel Beckman Foundation
- Columbia University
- Empire State Development's Division of Science, Technology and Innovation
- National Institutes of Health
- Canadian Institutes of Health Research
- Division of Chemistry
Citations
17,296
FWCI
47.37
field-weighted impact
References
55
Percentile
100%
vs. same field & year
Citations per year
Cited by
Parthanatos: mitochondrial‐linked mechanisms and therapeutic opportunities
British Journal of Pharmacology · 2013 · 582 citations
Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells
American Journal of Physiology-Renal Physiology · 2017 · 362 citations
The Metabolic Underpinnings of Ferroptosis
Cell Metabolism · 2020 · 1,298 citations
Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells
Cell Death and Disease · 2018 · 528 citations
Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
Oncotarget · 2015 · 597 citations
Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics
Journal of Neurochemistry · 2015 · 569 citations
Ferroptosis in Cancer Cell Biology
Cancers · 2020 · 336 citations
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
eLife · 2014 · 2,015 citations
References
Pyroptosis: host cell death and inflammation
Nature Reviews Microbiology · 2009 · 3,189 citations
Necroptosis as an alternative form of programmed cell death
Current Opinion in Cell Biology · 2010 · 779 citations
Rapid Communication: Oxidative Stress Induces Apoptosis in Embryonic Cortical Neurons
Journal of Neurochemistry · 1994 · 583 citations
Glutamate neurotoxicity and diseases of the nervous system
Neuron · 1988 · 8,002 citations
Antioxidant Determinations by the Use of a Stable Free Radical
Nature · 1958 · 12,578 citations
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
Cancer Cell · 2003 · 1,396 citations
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
Advanced Drug Delivery Reviews · 2001 · 17,620 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
