article Open AccessTop 1% cited
Glutaminolysis and Transferrin Regulate Ferroptosis
Molecular Cell · 2015 · Vol. 59(2) · pp. 298–308
Minghui Gao✉(Memorial Sloan Kettering Cancer Center)Prashant Monian(Memorial Sloan Kettering Cancer Center)Nosirudeen QuadriRavichandran Ramasamy(NYU Langone Health)Xuejun Jiang(Memorial Sloan Kettering Cancer Center)
Ferroptosis and cancer prognosisImmune cells in cancerBladder and Urothelial Cancer TreatmentsGlutaminolysisBiologyGlutamineTransferrinCell biologyTransferrin receptorProgrammed cell deathApoptosisBiochemistryAmino acid
MeSH terms
AnimalsCells, CulturedCulture MediaCystineGlutamineGlutathioneHumansIronMaleMice, Inbred C57BLNecrosisOxidation-ReductionReceptors, TransferrinTransferrinMyocardial Reperfusion Injury
Citations
1,981
FWCI
32.29
field-weighted impact
References
48
Percentile
100%
vs. same field & year
Citations per year
Cited by
The Metabolic Underpinnings of Ferroptosis
Cell Metabolism · 2020 · 1,298 citations
Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells
Cell Death and Disease · 2018 · 528 citations
Ferroptosis in Cancer Cell Biology
Cancers · 2020 · 336 citations
The Role of Ferroptosis in Cancer Development and Treatment Response
Frontiers in Pharmacology · 2018 · 460 citations
RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer
Frontiers in Pharmacology · 2018 · 685 citations
Targeting ferroptosis as a vulnerability in cancer
Nature reviews. Cancer · 2022 · 2,045 citations
Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes
Cell Death and Disease · 2019 · 349 citations
Ferroptosis Inhibition: Mechanisms and Opportunities
Trends in Pharmacological Sciences · 2017 · 565 citations
References
Cell Death
Cell · 2004 · 4,620 citations
Pyroptosis: host cell death and inflammation
Nature Reviews Microbiology · 2009 · 3,189 citations
Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method
Nature Protocols · 2006 · 2,181 citations
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Cell · 2012 · 17,296 citations
Regulation of Ferroptotic Cancer Cell Death by GPX4
Cell · 2014 · 7,213 citations
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
Cell Metabolism · 2008 · 4,067 citations
Antioxidant Determinations by the Use of a Stable Free Radical
Nature · 1958 · 12,578 citations
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Nature Cell Biology · 2014 · 3,521 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
