review Open AccessTop 1% cited
Caspase structure, proteolytic substrates, and function during apoptotic cell death
Cell Death and Differentiation · 1999 · Vol. 6(11) · pp. 1028–1042
DW Nicholson✉(Merck Canada Inc. (Canada))
Cell death mechanisms and regulationTrace Elements in HealthNF-κB Signaling PathwaysProteasesCaspaseApoptosisProgrammed cell deathCell biologyCaspase 2BiologyNLRP1Function (biology)Proteolytic enzymes
MeSH terms
Amino Acid SequenceAnimalsBinding SitesEnzyme ActivationHumansMolecular Sequence DataSubstrate SpecificityApoptosisCaspasesCaspase 1Caspase Inhibitors
Citations
1,540
FWCI
34.17
field-weighted impact
References
208
Percentile
100%
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Citations per year
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References
Attenuation of Delayed Neuronal Death after Mild Focal Ischemia in Mice by Inhibition of the Caspase Family
Journal of Cerebral Blood Flow & Metabolism · 1998 · 546 citations
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Cell · 1998 · 4,423 citations
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
The EMBO Journal · 1998 · 1,385 citations
Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis
The Journal of Pathology · 1999 · 642 citations
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Cell · 1997 · 7,227 citations
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
The EMBO Journal · 1997 · 1,297 citations
A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B
Journal of Biological Chemistry · 1997 · 2,071 citations
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