article Open AccessTop 1% cited
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Cell · 1997 · Vol. 91(4) · pp. 479–489
Peng Li✉Deepak Nijhawan(The University of Texas Southwestern Medical Center)I. Imawati Budihardjo(Howard Hughes Medical Institute)Srinivasa M. Srinivasula(Thomas Jefferson University)Manzoor Ahmad(Thomas Jefferson University)Emad S. Alnemri(Thomas Jefferson University)Xiaodong Wang(The University of Texas Southwestern Medical Center)
Cell death mechanisms and regulationMitochondrial Function and PathologyATP Synthase and ATPases ResearchBiologyCaspaseApoptosisCytochrome cApoptosomeCascadeCell biologyProteaseCytochromeCaspase-9
MeSH terms
Amino Acid SequenceBinding SitesBreast NeoplasmsCell LineCysteine EndopeptidasesCytochrome c GroupDeoxyadenine NucleotidesEnzyme ActivationEpithelial CellsHeLa CellsHumansKidneyModels, ChemicalMolecular Sequence DataMultienzyme Complexes
Citations
7,227
FWCI
126.22
field-weighted impact
References
63
Percentile
100%
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Citations per year
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References
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Cell · 1993 · 5,997 citations
Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis
The Journal of Experimental Medicine · 1997 · 1,859 citations
Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c
Cell · 1996 · 5,154 citations
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