review Open AccessTop 1% cited
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
Nature Immunology · 2009 · Vol. 10(3) · pp. 241–247
Luigi Franchi✉Tatjana Eigenbrod(University of Michigan–Ann Arbor)Raúl Muñoz-Planillo(University of Michigan–Ann Arbor)Gabriel Núñez(University of Michigan–Ann Arbor)
Inflammasome and immune disordersKawasaki Disease and Coronary ComplicationsHeme Oxygenase-1 and Carbon MonoxideInflammasomePyroptosisNLRC4Proinflammatory cytokineCaspase 1SecretionPathogenesisAIM2Cell biologyBiology
MeSH terms
NLR ProteinsNLR Family, Pyrin Domain-Containing 3 ProteinCalcium-Binding ProteinsCarrier ProteinsHumansUric AcidCaspase 1Adaptor Proteins, Signal TransducingApoptosis Regulatory ProteinsCARD Signaling Adaptor ProteinsInterleukin-1betaProtein Interaction Domains and Motifs
Funding
- Arthritis Foundation
Citations
1,825
FWCI
50.15
field-weighted impact
References
101
Percentile
100%
vs. same field & year
Citations per year
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References
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
Cell Death and Differentiation · 2007 · 1,418 citations
Pathogen Recognition and Innate Immunity
Cell · 2006 · 11,743 citations
Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages
PLoS Pathogens · 2007 · 530 citations
Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor
The EMBO Journal · 2006 · 1,427 citations
The immune gene repertoire encoded in the purple sea urchin genome
Developmental Biology · 2006 · 635 citations
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Nature Immunology · 2008 · 2,375 citations
IL‐1, IL‐18, and IL‐33 families of cytokines
Immunological Reviews · 2008 · 892 citations
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