reviewTop 1% cited
The proteasome: a novel target for cancer chemotherapy
Leukemia · 2002 · Vol. 16(4) · pp. 433–443
Ubiquitin and proteasome pathwaysCell death mechanisms and regulationCancer-related Molecular PathwaysProteasomeApoptosisBiologyCancer cellIntrinsic apoptosisCaspaseCancer researchCell biologyProteasome inhibitorCytochrome c
MeSH terms
AnimalsAntineoplastic AgentsCysteine EndopeptidasesEnzyme InhibitorsHumansMultienzyme ComplexesNeoplasmsApoptosisProteasome Endopeptidase Complex
Funding
- Medical Research Council
Citations
540
FWCI
12.67
field-weighted impact
References
88
Percentile
99%
vs. same field & year
Citations per year
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References
Caspases: the executioners of apoptosis
Biochemical Journal · 1997 · 4,725 citations
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
Annual Review of Biochemistry · 1999 · 2,764 citations
p27kip1: A Multifunctional Cyclin-Dependent Kinase Inhibitor with Prognostic Significance in Human Cancers
American Journal Of Pathology · 1999 · 590 citations
Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids
Bioorganic & Medicinal Chemistry Letters · 1998 · 680 citations
p53 Mutations in Human Cancers
Science · 1991 · 8,098 citations
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Cell · 1997 · 7,227 citations
Caspase structure, proteolytic substrates, and function during apoptotic cell death
Cell Death and Differentiation · 1999 · 1,540 citations
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
Annual Review of Immunology · 2000 · 4,725 citations
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