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The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

The EMBO Journal · 1997 · Vol. 16(23) · pp. 6914–6925
Natalie Roy
Cell death mechanisms and regulationAutophagy in Disease and TherapyCRISPR and Genetic EngineeringXIAPCaspaseProteasesBiologyInhibitor of apoptosisProgrammed cell deathCytochrome cApoptosisCell biologyInhibitor of apoptosis domain

MeSH terms

Antineoplastic Agents, PhytogenicCysteine EndopeptidasesCytochrome c GroupCytosolEnzyme ActivationEtoposideHumansProtein BindingProtein Processing, Post-TranslationalRecombinant ProteinsSignal TransductionCysteine Proteinase InhibitorsApoptosisCaspasesUbiquitin-Protein Ligases

Funding

  • National Institutes of Health
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