review Open AccessTop 1% cited
The Metabolic Underpinnings of Ferroptosis
Cell Metabolism · 2020 · Vol. 32(6) · pp. 920–937
Jiashuo Zheng(Helmholtz Zentrum München)Marcus Conrad✉(Pirogov Russian National Research Medical University)
Ferroptosis and cancer prognosisCancer, Lipids, and MetabolismDrug Transport and Resistance MechanismsProgrammed cell deathGPX4MitochondrionCell metabolismOxidative stressCell biologyLipid peroxidationApoptosisBiologyCell
Funding
- Deutsche Forschungsgemeinschaft
- Else Kröner-Fresenius-Stiftung
- Bundesministerium für Forschung und Technologie
- Russian Science Foundation
Citations
1,298
FWCI
78.48
field-weighted impact
References
283
Percentile
100%
vs. same field & year
Citations per year
Cited by
Targeting ferroptosis as a vulnerability in cancer
Nature reviews. Cancer · 2022 · 2,045 citations
The interaction between ferroptosis and inflammatory signaling pathways
Cell Death and Disease · 2023 · 451 citations
The hallmarks of cancer metabolism: Still emerging
Cell Metabolism · 2022 · 1,290 citations
The multifaceted role of ferroptosis in liver disease
Cell Death and Differentiation · 2022 · 621 citations
References
Glutaminolysis and Transferrin Regulate Ferroptosis
Molecular Cell · 2015 · 1,981 citations
The thioredoxin antioxidant system
Free Radical Biology and Medicine · 2013 · 1,975 citations
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Cell · 2012 · 17,296 citations
Regulation of Ferroptotic Cancer Cell Death by GPX4
Cell · 2014 · 7,213 citations
Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
Cell Metabolism · 2008 · 1,415 citations
Development of small-molecule probes that selectively kill cells induced to express mutant RAS
Bioorganic & Medicinal Chemistry Letters · 2011 · 234 citations
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Nature Cell Biology · 2014 · 3,521 citations
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
Cancer Cell · 2003 · 1,396 citations
Related articles
Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review
Frontiers in Physiology · 2019 · 514 citations
Ferroptosis Inhibition: Mechanisms and Opportunities
Trends in Pharmacological Sciences · 2017 · 565 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.