reviewTop 1% cited
Lipid peroxidation and ferroptosis: The role of GSH and GPx4
Free Radical Biology and Medicine · 2020 · Vol. 152 · pp. 175–185
Fulvio Ursini✉(University of Padua)Matilde Maiorino(University of Padua)
Ferroptosis and cancer prognosisCancer, Lipids, and MetabolismCholesterol and Lipid MetabolismGPX4Lipid peroxidationGlutathioneChemistryBiochemistryAntioxidantEnzyme
MeSH terms
FerroptosisPhospholipid Hydroperoxide Glutathione PeroxidaseLipid PeroxidationCell DeathApoptosis
Funding
- Educational Audiology Association
Citations
1,742
FWCI
91.39
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126
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100%
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References
The labile iron pool: characterization, measurement, and participation in cellular processes1 1This article is part of a series of reviews on “Iron and Cellular Redox Status.” The full list of papers may be found on the homepage of the journal.
Free Radical Biology and Medicine · 2002 · 823 citations
Glutaminolysis and Transferrin Regulate Ferroptosis
Molecular Cell · 2015 · 1,981 citations
Oxygen toxicity, oxygen radicals, transition metals and disease
Biochemical Journal · 1984 · 5,312 citations
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Cell · 2012 · 17,296 citations
Regulation of Ferroptotic Cancer Cell Death by GPX4
Cell · 2014 · 7,213 citations
Molecular mechanism activating nrf2–keap1 pathway in regulation of adaptive response to electrophiles
Free Radical Biology and Medicine · 2004 · 854 citations
Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Nature Cell Biology · 2014 · 3,521 citations
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