review Open AccessTop 1% cited
Targeting Ferroptosis to Iron Out Cancer
Cancer Cell · 2019 · Vol. 35(6) · pp. 830–849
Behrouz Hassannia✉(Ghent University)Peter Vandenabeele(Ghent University)Tom Vanden Berghe(University of Antwerp)
Ferroptosis and cancer prognosisCancer, Lipids, and MetabolismRNA modifications and cancerCancer researchCancer cellCancerBiologyGenetics
MeSH terms
FerroptosisAnimalsAntineoplastic AgentsHumansIronNeoplasmsLipid PeroxidationSignal TransductionDrug Resistance, NeoplasmMolecular Targeted Therapy
Funding
- University of Seoul
- Fonds Wetenschappelijk Onderzoek
- Universiteit Gent
- Vlaams Instituut voor Biotechnologie
- Stichting Tegen Kanker
- Fondation Charcot
- Universiteit Antwerpen
- Fondation contre le Cancer
Citations
2,515
FWCI
196.00
field-weighted impact
References
162
Percentile
100%
vs. same field & year
Citations per year
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References
Glutaminolysis and Transferrin Regulate Ferroptosis
Molecular Cell · 2015 · 1,981 citations
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Nature Reviews Drug Discovery · 2009 · 5,229 citations
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Cell · 2012 · 17,296 citations
Regulation of Ferroptotic Cancer Cell Death by GPX4
Cell · 2014 · 7,213 citations
Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
Cell Metabolism · 2008 · 1,415 citations
Development of small-molecule probes that selectively kill cells induced to express mutant RAS
Bioorganic & Medicinal Chemistry Letters · 2011 · 234 citations
The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress
Journal of Biological Chemistry · 2009 · 2,633 citations
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Nature Cell Biology · 2014 · 3,521 citations
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