review Open AccessTop 1% cited
Ferroptosis: mechanisms, biology and role in disease
Nature Reviews Molecular Cell Biology · 2021 · Vol. 22(4) · pp. 266–282
Xuejun Jiang✉(Memorial Sloan Kettering Cancer Center)Brent R. Stockwell✉(Columbia University)Marcus Conrad✉(Helmholtz Zentrum München)
Ferroptosis and cancer prognosisCancer, Lipids, and MetabolismRNA modifications and cancerDiseaseGPX4Lipid peroxidationMechanism (biology)Programmed cell deathBiologyImmune systemNeuroscienceCancer cellCancer
MeSH terms
FerroptosisAnimalsHumansNeoplasmsOxidation-ReductionReproducibility of ResultsLipid PeroxidationGene Regulatory Networks
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References
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Molecular Cell · 2015 · 1,981 citations
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Physiological Reviews · 2014 · 1,805 citations
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Cell · 2012 · 17,296 citations
Regulation of Ferroptotic Cancer Cell Death by GPX4
Cell · 2014 · 7,213 citations
The Hippo Signaling Pathway in Development and Cancer
Developmental Cell · 2010 · 2,278 citations
Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
Cell Metabolism · 2008 · 1,415 citations
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Nature Cell Biology · 2014 · 3,521 citations
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
British Journal of Cancer · 1972 · 15,557 citations
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