review Open AccessTop 1% cited
Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario
Cell Death and Differentiation · 2006 · Vol. 13(8) · pp. 1396–1402
Jerry E. Chipuk✉(St. Jude Children's Research Hospital)Lisa Bouchier‐Hayes(St. Jude Children's Research Hospital)Douglas R. Green(St. Jude Children's Research Hospital)
Cell death mechanisms and regulationMitochondrial Function and PathologyATP Synthase and ATPases ResearchCell biologyCytosolMitochondrionBystander effectApoptosisProgrammed cell deathBacterial outer membraneCytochrome cBiologyMitochondrial apoptosis-induced channel
MeSH terms
AnimalsHumansPermeabilityApoptosisProto-Oncogene Proteins c-bcl-2CaspasesBystander EffectMitochondrial Membranes
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References
Cell Death
Cell · 2004 · 4,620 citations
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
Cancer Cell · 2002 · 1,634 citations
PUMA, a Novel Proapoptotic Gene, Is Induced by p53
Molecular Cell · 2001 · 2,283 citations
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Cell · 1998 · 4,423 citations
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
The EMBO Journal · 1998 · 1,231 citations
Bcl-2-family proteins and the role of mitochondria in apoptosis
Current Opinion in Cell Biology · 2003 · 628 citations
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Cell · 1997 · 7,227 citations
Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function
Molecular Cell · 2005 · 1,794 citations
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