article Open AccessTop 1% cited
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
The EMBO Journal · 1998 · Vol. 17(1) · pp. 37–49
Ella Bossy‐Wetzel✉(La Jolla Institute for Immunology)
Cell death mechanisms and regulationNF-κB Signaling Pathwaysinterferon and immune responsesCytochrome cClinical immunologyApoptosisImmunologyBiologyAllergyBiochemistry
MeSH terms
Amino Acid Chloromethyl KetonesBiological TransportCell LineCysteine EndopeptidasesCytochrome c GroupCytosolEnzyme ActivationHumansMembrane PotentialsMitochondriaOligopeptidesTumor Cells, CulturedUltraviolet RaysCysteine Proteinase InhibitorsApoptosis
Funding
- National Science Foundation
- American Cancer Society
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- National Institutes of Health
Citations
1,231
FWCI
60.62
field-weighted impact
References
113
Percentile
100%
vs. same field & year
Citations per year
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References
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
Neuron · 1995 · 1,882 citations
Apoptosis by Death Factor
Cell · 1997 · 4,983 citations
Shrinkage necrosis: A distinct mode of cellular death
The Journal of Pathology · 1971 · 1,455 citations
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.
The Journal of Experimental Medicine · 1995 · 1,564 citations
Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis
The Journal of Experimental Medicine · 1997 · 1,859 citations
Aging, energy, and oxidative stress in neurodegenerative diseases
Annals of Neurology · 1995 · 1,440 citations
Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c
Cell · 1996 · 5,154 citations
THE MITOCHONDRIAL ELECTRON TRANSPORT AND OXIDATIVE PHOSPHORYLATION SYSTEM
Annual Review of Biochemistry · 1985 · 1,645 citations
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