article Open AccessTop 1% cited
PUMA, a Novel Proapoptotic Gene, Is Induced by p53
Molecular Cell · 2001 · Vol. 7(3) · pp. 683–694
Katsunori Nakano(Frederick National Laboratory for Cancer Research)Karen H. Vousden✉(Frederick National Laboratory for Cancer Research)
Cancer-related Molecular PathwaysCell death mechanisms and regulationMolecular Biology Techniques and ApplicationsPumaBiologyApoptosisCell biologyActivator (genetics)Programmed cell deathGeneCytochrome cRegulation of gene expressionMolecular biology
MeSH terms
Amino Acid SequenceBase SequenceBinding SitesCell DivisionCell LineCloning, MolecularCytochrome c GroupDNAEnzyme ActivationEnzyme PrecursorsExonsHumansIntronsMitochondriaMolecular Sequence Data
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References
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The Journal of Pathology · 1999 · 1,303 citations
Bcl-2 family proteins
Oncogene · 1998 · 1,055 citations
PUMA Induces the Rapid Apoptosis of Colorectal Cancer Cells
Molecular Cell · 2001 · 1,277 citations
Mitochondria and Apoptosis
Science · 1998 · 8,971 citations
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
The EMBO Journal · 1998 · 1,166 citations
Apoptosis in cancer
Carcinogenesis · 2000 · 1,870 citations
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