review Open AccessTop 1% cited
Pyroptosis: host cell death and inflammation
Nature Reviews Microbiology · 2009 · Vol. 7(2) · pp. 99–109
Tessa Bergsbaken✉(University of Washington)Susan L. Fink(University of Washington)Brad T. Cookson(University of Washington)
Inflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideGout, Hyperuricemia, Uric AcidPyroptosisBiologyProgrammed cell deathProinflammatory cytokineInflammationNecroptosisCaspase 1InflammasomeCell biologyImmunology
MeSH terms
AnimalsFeverHumansInflammationApoptosisCaspase 1Mice
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References
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
Cell Death and Differentiation · 2007 · 1,418 citations
Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity
PLoS Pathogens · 2006 · 535 citations
<i>Salmonella</i> induces macrophage death by caspase‐1‐dependent necrosis
Molecular Microbiology · 2000 · 676 citations
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
British Journal of Cancer · 1972 · 15,557 citations
Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages
PLoS Pathogens · 2007 · 530 citations
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
Cell Death and Differentiation · 2007 · 1,018 citations
Inflammatory caspases and inflammasomes: master switches of inflammation
Cell Death and Differentiation · 2006 · 819 citations
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