reviewTop 1% cited
Genomic instability — an evolving hallmark of cancer
Nature Reviews Molecular Cell Biology · 2010 · Vol. 11(3) · pp. 220–228
Simona NegriniVassilis G. Gorgoulis(University of Geneva)Thanos D. Halazonetis✉(National and Kapodistrian University of Athens)
DNA Repair MechanismsCancer-related Molecular PathwaysMicrotubule and mitosis dynamicsGenome instabilityBiologyCDKN2AGeneticsDNA repairCancer researchgenomic DNAMutationCancerGene
MeSH terms
AnimalsDNA DamageDNA-Binding ProteinsHumansModels, BiologicalMutationNeoplasmsTumor Suppressor Protein p53Protein Serine-Threonine KinasesCell Cycle ProteinsCyclin-Dependent Kinase Inhibitor p16Tumor Suppressor ProteinsGenomic InstabilityAtaxia Telangiectasia Mutated Proteins
Funding
- Foundation for the National Institutes of Health
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- H2020 European Research Council
Citations
2,355
FWCI
53.42
field-weighted impact
References
65
Percentile
100%
vs. same field & year
Citations per year
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References
Tumor Cell Metabolism: Cancer's Achilles' Heel
Cancer Cell · 2008 · 2,271 citations
A genetic model for colorectal tumorigenesis
Cell · 1990 · 12,052 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
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