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Modulation of oxidative stress as an anticancer strategy

Nature Reviews Drug Discovery · 2013 · Vol. 12(12) · pp. 931–947
Chiara GorriniIsaac S. HarrisTak W. Mak
Cancer, Hypoxia, and MetabolismRedox biology and oxidative stressGenomics, phytochemicals, and oxidative stressOxidative stressCarcinogenesisReactive oxygen speciesDNA damageCell biologyCancer cellCancer researchSignal transductionBiologyHedgehog signaling pathway

MeSH terms

AnimalsAntineoplastic AgentsHumansNeoplasmsReactive Oxygen SpeciesOxidative Stress

Funding

  • Canadian Institutes of Health Research
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References
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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Nature Reviews Drug Discovery · 2009 · 5,229 citations
5-Fluorouracil: mechanisms of action and clinical strategies
Nature reviews. Cancer · 2003 · 5,181 citations
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