reviewTop 1% cited

Regulation of cancer cell metabolism

Nature reviews. Cancer · 2011 · Vol. 11(2) · pp. 85–95

Rob A. Cairns✉Isaac S. Harris(Ontario Institute for Cancer Research)Tak W. Mak(Ontario Institute for Cancer Research)

Cancer, Hypoxia, and Metabolism Metabolism, Diabetes, and Cancer ATP Synthase and ATPases ResearchWarburg effectCarcinogenesisBiologyCancerCancer cellOncogeneMetabolismMetabolic pathwayTumor microenvironmentCell metabolism

MeSH terms

Cell Transformation, NeoplasticHumansNeoplasmsOxidation-ReductionTranscription FactorsSignal TransductionGene Expression Regulation, NeoplasticIntracellular Signaling Peptides and ProteinsGene Regulatory Networks

Citations

4,732

FWCI

96.73

field-weighted impact

References

145

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100%

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Citations per year

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References

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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

Nature Reviews Drug Discovery · 2009 · 5,229 citations

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

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