articleTop 1% cited
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
Advanced Drug Delivery Reviews · 2012 · Vol. 64 · pp. 138–153
Alfred H. Schinkel✉(The Netherlands Cancer Institute)Johan W. Jonker(The Netherlands Cancer Institute)
Drug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesPregnancy and Medication ImpactATP-binding cassette transporterEffluxDrugTransporterPharmacologyBioavailabilityMultidrug resistance-associated protein 2BiologyChemistryBiochemistry
Funding
- KWF Kankerbestrijding
Citations
1,226
FWCI
44.90
field-weighted impact
References
204
Percentile
100%
vs. same field & year
Citations per year
Cited by
Epithelial Mesenchymal Transition in Embryonic Development, Tissue Repair and Cancer: A Comprehensive Overview
Journal of Clinical Medicine · 2017 · 297 citations
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade
Cancer Letters · 2015 · 711 citations
Importance of P-glycoprotein at blood–tissue barriers
Trends in Pharmacological Sciences · 2004 · 582 citations
A review of the dietary flavonoid, kaempferol on human health and cancer chemoprevention
Food Chemistry · 2012 · 969 citations
Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications
Pharmaceutical Research · 2007 · 980 citations
Membrane transporters in drug development
Nature Reviews Drug Discovery · 2010 · 3,297 citations
Targeting multidrug resistance in cancer
Nature Reviews Drug Discovery · 2006 · 3,630 citations
References
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
Nature Medicine · 2001 · 2,273 citations
Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells
Molecular Pharmacology · 1999 · 680 citations
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 801 citations
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3,268 citations
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
Cellular and Molecular Life Sciences · 2001 · 685 citations
A Family of Drug Transporters: the Multidrug Resistance-Associated Proteins
JNCI Journal of the National Cancer Institute · 2000 · 1,754 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.