articleTop 1% cited

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Nature Medicine · 2001 · Vol. 7(9) · pp. 1028–1034

Sheng Zhou✉(St. Jude Children's Research Hospital)John D. Schuetz(St. Jude Children's Research Hospital)Kevin D. Bunting(St. Jude Children's Research Hospital)Anne-Marie Colapietro(St. Jude Children's Research Hospital)Janardhan Sampath(St. Jude Children's Research Hospital)John J. Morris(St. Jude Children's Research Hospital)Irina V. Lagutina(St. Jude Children's Research Hospital)Gerard C. Grosveld(St. Jude Children's Research Hospital)Mitsujiro Osawa(University of Tsukuba)Hiromitsu Nakauchi(University of Tsukuba)Brian P. Sorrentino(St. Jude Children's Research Hospital)

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Drug Transport and Resistance Mechanisms RNA Interference and Gene Delivery Hemoglobinopathies and Related DisordersStem cellPhenotypeBiologySide populationHaematopoiesisAbcg2Molecular biologyBone marrowPopulationATP-binding cassette transporter

MeSH terms

ATP Binding Cassette Transporter, Subfamily G, Member 2AnimalsBone Marrow CellsCells, CulturedFemaleHumansMaleMembrane GlycoproteinsMice, Inbred StrainsMice, Mutant StrainsNeoplasm ProteinsRibosomal ProteinsStem CellsBiomarkersAntigens, CD

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview