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Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications

Pharmaceutical Research · 2007 · Vol. 24(7) · pp. 1227–1251
Hermann KoepsellKatrin Susanne LipsChristopher Volk
Drug Transport and Resistance MechanismsAmino Acid Enzymes and MetabolismChemical Reaction MechanismsOrganic cation transport proteinsTransporterSolute carrier familyOrganic anion transporter 1ATP-binding cassette transporterChemistryPharmacologyEffluxEpithelial polarityApical membrane

MeSH terms

AnimalsBinding SitesBiopharmaceuticsCationsCloning, MolecularDrug InteractionsPharmaceutical PreparationsHumansModels, MolecularPharmacokineticsPolymorphism, GeneticProtein ConformationStructure-Activity RelationshipTissue DistributionNeurotransmitter Agents
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