reviewTop 1% cited
Importance of P-glycoprotein at blood–tissue barriers
Trends in Pharmacological Sciences · 2004 · Vol. 25(8) · pp. 423–429
Martin F. Fromm✉(Friedrich-Alexander-Universität Erlangen-Nürnberg)
Drug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesPediatric Hepatobiliary Diseases and TreatmentsP-glycoproteinGlycoproteinPlacentaEffluxAbcg2Excretory systemTransporterXenobioticATP-binding cassette transporterBiology
MeSH terms
AnimalsBlood-Brain BarrierBlood-Testis BarrierPharmaceutical PreparationsHumansIntestinal MucosaKidneyLiverPharmacokineticsPlacentaATP Binding Cassette Transporter, Subfamily B, Member 1
Funding
- Deutsche Forschungsgemeinschaft
Citations
582
FWCI
17.51
field-weighted impact
References
85
Percentile
100%
vs. same field & year
Citations per year
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Nature reviews. Cancer · 2002 · 5,468 citations
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
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Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.
Journal of Histochemistry & Cytochemistry · 1990 · 1,070 citations
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
Clinical Pharmacology & Therapeutics · 2001 · 749 citations
Identification of functionally variant MDR1 alleles among European Americans and African Americans
Clinical Pharmacology & Therapeutics · 2001 · 1,008 citations
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
Advanced Drug Delivery Reviews · 2003 · 1,359 citations
Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)*1
Clinical Pharmacology & Therapeutics · 1999 · 588 citations
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