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From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

Cellular and Molecular Life Sciences · 2001 · Vol. 58(7) · pp. 931–959
Thomas LitmanTodd E. DruleyWilfred D. SteinSusan E. Bates
Drug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesHIV/AIDS drug development and treatmentATP-binding cassette transporterMultiple drug resistanceAbcg2P-glycoproteinEffluxTransporterFunction (biology)BiologyMechanism of actionDrug resistance

MeSH terms

ATP Binding Cassette Transporter, Subfamily G, Member 2AnimalsAntineoplastic AgentsForecastingHumansMitoxantroneNeoplasm ProteinsDrug Resistance, MultipleATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily B, Member 1
Citations
685
FWCI
21.39
field-weighted impact
References
223
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100%
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From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance · Scinovex