article Open AccessTop 1% cited
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Cell · 2015 · Vol. 163(3) · pp. 759–771
Bernd Zetsche✉(Broad Institute)Jonathan S. Gootenberg(Broad Institute)Omar O. Abudayyeh(Broad Institute)Ian M. Slaymaker(Broad Institute)Kira S. Makarova(National Institutes of Health)Patrick Essletzbichler(Broad Institute)Sara E. Volz(Broad Institute)Julia Joung(Broad Institute)John van der Oost(Wageningen University & Research)Aviv Regev(Broad Institute)Eugene V. Koonin(National Institutes of Health)Feng Zhang(Broad Institute)
CRISPR and Genetic EngineeringInnovation and Socioeconomic DevelopmentViral Infections and Immunology ResearchBiologyCRISPREndonucleaseGeneticsComputational biologyRNAClass (philosophy)DNAGeneComputer science
MeSH terms
CRISPR-Cas SystemsRNA, Guide, CRISPR-Cas SystemsAmino Acid SequenceEndonucleasesFrancisellaGenetic EngineeringHumansMolecular Sequence DataNucleic Acid ConformationSequence AlignmentRNA, Guide, KinetoplastidaHEK293 Cells
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Nature Biotechnology · 2013 · 4,831 citations
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Science · 2012 · 16,935 citations
Multiplex Genome Engineering Using CRISPR/Cas Systems
Science · 2013 · 15,534 citations
Development and Applications of CRISPR-Cas9 for Genome Engineering
Cell · 2014 · 5,789 citations
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Bioinformatics · 2009 · 61,752 citations
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