article Open AccessTop 1% cited
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
Nature Protocols · 2017 · Vol. 12(4) · pp. 828–863
Julia Joung✉(Broad Institute)Silvana Konermann(Broad Institute)Jonathan S. Gootenberg(Broad Institute)Omar O. Abudayyeh(Broad Institute)Randall J. Platt(Broad Institute)Mark D. Brigham(Broad Institute)Neville E. Sanjana(Broad Institute)Feng Zhang(Broad Institute)
CRISPR and Genetic EngineeringRNA and protein synthesis mechanismsRNA Interference and Gene DeliveryCRISPRCas9BiologyComputational biologyGenome editingGenomeGuide RNAGeneticsGenetic screenIndel
MeSH terms
AnimalsGenetic VectorsHumansPhenotypeTranscriptional ActivationGene LibraryLentivirusGenomicsMiceGene Knockout TechniquesCRISPR-Cas Systems
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References
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