review Open AccessTop 1% cited
Base editing: precision chemistry on the genome and transcriptome of living cells
Nature Reviews Genetics · 2018 · Vol. 19(12) · pp. 770–788
Holly A. Rees✉(Broad Institute)David R. Liu(Broad Institute)
CRISPR and Genetic EngineeringRNA regulation and diseaseAdvanced biosensing and bioanalysis techniquesRNA editingRNAGenome editingBiologyCRISPRComputational biologyDNADNA glycosylaseBase pairPoint mutation
MeSH terms
EndonucleasesHumansGene EditingAnimalsDNA Breaks, Double-StrandedTranscriptomeCRISPR-Cas Systems
Citations
1,652
FWCI
64.59
field-weighted impact
References
172
Percentile
100%
vs. same field & year
Citations per year
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References
Genome engineering using the CRISPR-Cas9 system
Nature Protocols · 2013 · 11,552 citations
RNA-Guided Human Genome Engineering via Cas9
Science · 2013 · 9,293 citations
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Nature Biotechnology · 2014 · 2,254 citations
Progress and problems with the use of viral vectors for gene therapy
Nature Reviews Genetics · 2003 · 2,489 citations
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Science · 2012 · 16,935 citations
Multiplex Genome Engineering Using CRISPR/Cas Systems
Science · 2013 · 15,534 citations
Codon—anticodon pairing: The wobble hypothesis
Journal of Molecular Biology · 1966 · 2,036 citations
Identification of genes that are associated with DNA repeats in prokaryotes
Molecular Microbiology · 2002 · 1,958 citations
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