article Open AccessTop 1% cited
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
Nature Genetics · 2015 · Vol. 47(3) · pp. 291–295
Brendan Bulik‐Sullivan✉(Broad Institute)Po‐Ru Loh(Broad Institute)Hilary K. Finucane(Massachusetts Department of Public Health)Stephan Ripke(Broad Institute)Jian Yang(The University of Queensland)Nick Patterson(Broad Institute)Mark J. Daly(Broad Institute)Alkes L. Price(Broad Institute)Benjamin M. Neale(Broad Institute)
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and AnimalsConfoundingBiologyGenome-wide association studyRegressionGenetic associationGeneticsComputational biologySingle-nucleotide polymorphismInternal medicineGene
MeSH terms
Computer SimulationHumansRegression AnalysisLinkage DisequilibriumGenome, HumanSample SizePolymorphism, Single NucleotideGenome-Wide Association Study
Funding
- National Institutes of Health
- Medical Research Council
Citations
6,093
FWCI
219.60
field-weighted impact
References
46
Percentile
100%
vs. same field & year
Citations per year
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References
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The American Journal of Human Genetics · 2001 · 1,311 citations
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GCTA: A Tool for Genome-wide Complex Trait Analysis
The American Journal of Human Genetics · 2010 · 9,109 citations
A mega-analysis of genome-wide association studies for major depressive disorder
Molecular Psychiatry · 2012 · 1,159 citations
Variance component model to account for sample structure in genome-wide association studies
Nature Genetics · 2010 · 3,011 citations
Population Structure and Eigenanalysis
PLoS Genetics · 2006 · 5,602 citations
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Nature Genetics · 2010 · 2,969 citations
Principal components analysis corrects for stratification in genome-wide association studies
Nature Genetics · 2006 · 10,603 citations
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