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A mega-analysis of genome-wide association studies for major depressive disorder

Molecular Psychiatry · 2012 · Vol. 18(4) · pp. 497–511

Stephan Ripke(Broad Institute)Naomi R. Wray(The University of Queensland)Cathryn M. Lewis(King's College London)Steven P. Hamilton(University of California, San Francisco)Myrna M. Weissman(Columbia University)Gerome Breen(King's College London)Enda M. Byrne(QIMR Berghofer Medical Research Institute)Douglas Blackwood(University of Edinburgh)Dorret I. BoomsmaSven Cichon(University of Bonn)Andrew C. Heath(Washington University in St. Louis)Florian Holsboer(Max Planck Institute of Psychiatry)Susanne Lucae(Max Planck Institute of Psychiatry)Pamela A. F. Madden(Washington University in St. Louis)Nicholas G. Martin(QIMR Berghofer Medical Research Institute)Peter McGuffin(King's College London)Pierandrea Muglia(GlaxoSmithKline (Italy))Markus M. Nöethen(University of Bonn)Brenda P Penninx(Amsterdam UMC Location Vrije Universiteit Amsterdam)Michele L. Pergadia(Washington University in St. Louis)James B. Potash(University of Iowa)Marcella Rietschel(Heidelberg University)D. Y. LinBertram Müller‐Myhsok(Max Planck Institute of Psychiatry)Jianxin Shi(National Cancer Institute)Stacy Steinberg(deCODE Genetics (Iceland))Hans J. Grabe(Universität Greifswald)Paul Lichtenstein(Karolinska Institutet)Patrik K. E. Magnusson(Karolinska Institutet)Roy H. Perlis(Massachusetts General Hospital)Martin Preisig(University of Lausanne)Jordan W. Smoller(Massachusetts General Hospital)Kāri Stefánsson(deCODE Genetics (Iceland))Rudolf Uher(King's College London)Zoltán Kutalik(University of Lausanne)Katherine E. Tansey(King's College London)Alexander Teumer(Universität Greifswald)Alexander Viktorin(Karolinska Institutet)Michael R. Barnes(GlaxoSmithKline (United Kingdom))Thomas Bettecken(Max Planck Institute of Psychiatry)Elisabeth B. Binder(Max Planck Institute of Psychiatry)René Breuer(Heidelberg University)Víctor M. Castro(Mass General Brigham)Susanne Churchill(Mass General Brigham)William Coryell(University of Iowa)Nick Craddock(Cardiff University)Ian Craig(King's College London)Darina Czamara(Max Planck Institute of Psychiatry)Eco J. C. de GeusFranziska Degenhardt(University of Bonn)Anne Farmer(King's College London)Maurizio Fava(Massachusetts General Hospital)Josef Frank(Heidelberg University)Vivian S. Gainer(Mass General Brigham)Patience Gallagher(Massachusetts General Hospital)Scott D. Gordon(QIMR Berghofer Medical Research Institute)Sergey Goryachev(Mass General Brigham)Magdalena Groß(University of Bonn)Michel Guipponi(University of Geneva)Anjali K. Henders(QIMR Berghofer Medical Research Institute)Stefan Herms(University of Bonn)Ian B. Hickie(The University of Sydney)Susanne Hoefels(University of Bonn)Witte J.G. Hoogendijk(Erasmus MC)Jouke‐Jan HottengaDan V. Iosifescu(Massachusetts General Hospital)Marcus Ising(Max Planck Institute of Psychiatry)Ian D. Jones(Cardiff University)Lisa Jones(University of Birmingham)Tzeng Jung-Ying(North Carolina State University)James A. Knowles(University of Southern California)Isaac S. Kohane(Brigham and Women's Hospital)Martin Kohli(Max Planck Institute of Psychiatry)Ania Korszun(Queen Mary University of London)Mikael Landén(Karolinska Institutet)William Lawson(Howard University)Glyn Lewis(University of Bristol)Donald J. MacIntyre(University of Edinburgh)Wolfgang Maier(University of Bonn)Manuel Mattheisen(University of Bonn)Patrick J. McGrath(Columbia University)Andrew M. McIntosh(University of Edinburgh)Alan McLean(University of Edinburgh)Christel M. MiddeldorpLefkos Middleton(Imperial College London)Grant W. Montgomery(QIMR Berghofer Medical Research Institute)Shawn N. Murphy(Massachusetts General Hospital)Matthias Nauck(Universität Greifswald)Willem A. Nolen(University Medical Center Groningen)Dale R. Nyholt(QIMR Berghofer Medical Research Institute)Michael O’Donovan(Cardiff University)Högni ÓskarssonNancy L. Pedersen(Karolinska Institutet)William A. Scheftner(Rush University Medical Center)Andrea Schulz(Universität Greifswald)Thomas G. SchulzeStanley I. Shyn(University of Washington)Engilbert Sigurðsson(National University Hospital of Iceland)Susan L. Slager(WinnMed)Johannes H. Smit(Amsterdam UMC Location Vrije Universiteit Amsterdam)Hreinn Stefánsson(deCODE Genetics (Iceland))Michael Steffens(University of Bonn)Thorgeir E. Thorgeirsson(deCODE Genetics (Iceland))Federica Tozzi(GlaxoSmithKline (Italy))Jens Treutlein(Heidelberg University)Manfred Uhr(Max Planck Institute of Psychiatry)Edwin J.C.G. van den Oord(Virginia Commonwealth University)Gerard van Grootheest(Amsterdam UMC Location Vrije Universiteit Amsterdam)Henry Völzke(Universität Greifswald)Jeffrey B. Weilburg(Massachusetts General Hospital)Gonneke WillemsenFrans G. Zitman(Leiden University Medical Center)Benjamin M. Neale(Broad Institute)Mark J. Daly(Broad Institute)Douglas F. Levinson(Stanford University)Patrick F. Sullivan✉

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Genetic Associations and Epidemiology Genetics and Neurodevelopmental Disorders Epigenetics and DNA MethylationMajor depressive disorderGenome-wide association studySingle-nucleotide polymorphismGenetic associationBipolar disorderOncologyGeneticsMedicinePsychiatryBiology

MeSH terms

Bipolar DisorderDepressive Disorder, MajorMajor Depressive DisorderFemaleHumansMaleCase-Control StudiesGenetic Predisposition to DiseasePolymorphism, Single NucleotideWhite PeopleGenome-Wide Association Study