articleTop 1% cited
Principal components analysis corrects for stratification in genome-wide association studies
Nature Genetics · 2006 · Vol. 38(8) · pp. 904–909
Alkes L. Price✉(Broad Institute)Nick J. Patterson(Broad Institute)Robert M. Plenge(Brigham and Women's Hospital)Michael E. Weinblatt(Brigham and Women's Hospital)Nancy A. Shadick(Brigham and Women's Hospital)David Reich(Harvard University)
Genetic Associations and EpidemiologyGenomic variations and chromosomal abnormalitiesGenetic Syndromes and ImprintingPopulation stratificationSpurious relationshipBiologyPrincipal component analysisAllele frequencyGenetic associationGenome-wide association studyPopulationEvolutionary biologyComputational biology
MeSH terms
AlgorithmsAllelesGenetic MarkersGenotypeHumansPhenotypeGenome, HumanCase-Control StudiesPolymorphism, Single NucleotideGenomicsPrincipal Component AnalysisDatabases, Nucleic Acid
Funding
- Takeda Oncology
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The American Journal of Human Genetics · 2004 · 1,182 citations
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