article Open AccessTop 1% cited
Leveraging Polygenic Functional Enrichment to Improve GWAS Power
The American Journal of Human Genetics · 2018 · Vol. 104(1) · pp. 65–75
Gleb Kichaev✉(University of California, Los Angeles)Gaurav Bhatia(Harvard University)Po‐Ru Loh(Harvard University)Steven Gazal(Broad Institute)Kathryn S. Burch(University of California, Los Angeles)Malika Freund(University of California, Los Angeles)Armin Schoech(Broad Institute)Bogdan Paşaniuc(University of California, Los Angeles)Alkes L. Price✉(Broad Institute)
Genetic Associations and EpidemiologyGenomics and Rare DiseasesGenetic Syndromes and ImprintingGenome-wide association studyComputer scienceComputational biologyBiologyGeneticsSingle-nucleotide polymorphismGenotype
MeSH terms
CalibrationFalse Positive ReactionsUnited KingdomHumansProbabilityReproducibility of ResultsMultifactorial InheritancePolymorphism, Single NucleotideDatabases, GeneticGenome-Wide Association StudyDatasets as Topic
Funding
- National Institutes of Health
- Medical Research Council
Citations
1,060
FWCI
83.00
field-weighted impact
References
55
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100%
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References
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Nature Genetics · 2015 · 6,093 citations
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Nature Genetics · 2010 · 4,788 citations
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