articleTop 1% cited
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
Advanced Drug Delivery Reviews · 2003 · Vol. 55(1) · pp. 3–29
Alfred H. Schinkel✉(The Netherlands Cancer Institute)Johan W. Jonker(The Netherlands Cancer Institute)
Drug Transport and Resistance MechanismsCholesterol and Lipid MetabolismPharmacogenetics and Drug MetabolismATP-binding cassette transporterEffluxTransporterDrugPharmacologyBioavailabilityMultidrug resistance-associated protein 2BiologyAbcg2Drug metabolism
MeSH terms
ATP Binding Cassette Transporter, Subfamily G, Member 2AnimalsBiological Transport, ActiveDrug InteractionsPharmaceutical PreparationsHumansMammalsNeoplasm ProteinsPharmacokineticsATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily B, Member 1Multidrug Resistance-Associated ProteinsATP-Binding Cassette, Sub-Family C Proteins
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References
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
Nature Medicine · 2001 · 2,273 citations
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 801 citations
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3,268 citations
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
Cellular and Molecular Life Sciences · 2001 · 685 citations
A Family of Drug Transporters: the Multidrug Resistance-Associated Proteins
JNCI Journal of the National Cancer Institute · 2000 · 1,754 citations
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