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Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

Molecular Cell · 2012 · Vol. 49(2) · pp. 359–367
Gregory HannumJustin GuinneyLing ZhaoLi ZhangGuy HughesSriniVas R. SaddaBrandy KlotzleMarina BibikovaJian-Bing FanYuan GaoRob DecondeMenzies ChenIndika RajapakseStephen FriendTrey IdekerKang Zhang
Epigenetics and DNA MethylationBirth, Development, and HealthRNA modifications and cancerBiologyDNA methylationGenomeComputational biologyMethylationGeneticsHuman genomeEvolutionary biologyGeneGene expression

MeSH terms

AdultAgedAged, 80 and overAgingFemaleHumansMaleMiddle AgedModels, GeneticPhenotypeGenome, HumanSequence Analysis, DNADNA MethylationEpigenesis, GeneticGenome-Wide Association Study

Funding

  • Burroughs Wellcome Fund
  • King Abdulaziz City for Science and Technology
  • University of California, San Diego
  • National Key Research and Development Program of China
Citations
4,325
FWCI
29.67
field-weighted impact
References
62
Percentile
100%
vs. same field & year
Citations per year
References
Cancer-epigenetics comes of age
Nature Genetics · 1999 · 2,354 citations
Epigenetics and aging: the targets and the marks
Trends in Genetics · 2007 · 687 citations
<i>The Mathematical Theory of Communication</i>
Physics Today · 1950 · 9,849 citations
Missing value estimation methods for DNA microarrays
Bioinformatics · 2001 · 4,180 citations
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1995 · 106,483 citations
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