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Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

Cell stem cell · 2013 · Vol. 13(6) · pp. 691–705
Justine D. MillerYosif GanatSarah KishinevskyRobert L. BowmanBecky LiuEdmund Y. TuPankaj Kumar MandalElsa VeraJaewon ShimSonja KriksTony TaldoneNoemi FusakiMark TomishimaDimitri KraincTeresa A. MilnerDerrick J. RossiLorenz Studer
Nuclear Structure and FunctionRNA Research and SplicingRNA Interference and Gene DeliveryBiologyDiseaseCell biologyNeuroscienceCancer researchInternal medicine

MeSH terms

AdultAgedAged, 80 and overAgingAnimalsCell DifferentiationChildFibroblastsHumansMesencephalonMiddle AgedModels, BiologicalNuclear ProteinsParkinson DiseasePhenotype

Funding

  • National Science Foundation
  • New York Stem Cell Foundation
  • Memorial Sloan-Kettering Cancer Center
  • National Institutes of Health
  • National Institute of Neurological Disorders and Stroke
Citations
755
FWCI
27.96
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References
291
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100%
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