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Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

Nature Reviews Drug Discovery · 2012 · Vol. 11(8) · pp. 633–652
Charles A. DinarelloAnna SimonJos W.M. van der Meer
Inflammasome and immune disordersIL-33, ST2, and ILC PathwaysAutoimmune and Inflammatory Disorders ResearchAnakinraCanakinumabMedicineImmunologyMonoclonal antibodyInflammationInterleukin 1 receptor antagonistReceptor antagonistCytokinePharmacology

MeSH terms

AnimalsAnti-Inflammatory AgentsAntibodies, MonoclonalAutoimmune DiseasesHumansInflammationInterleukin-1Recombinant Fusion ProteinsSeverity of Illness IndexDrug DesignDrug Delivery SystemsReceptors, Interleukin-1Interleukin 1 Receptor Antagonist ProteinAntibodies, Monoclonal, Humanized
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