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An inflammatory cytokine signature predicts COVID-19 severity and survival

Nature Medicine · 2020 · Vol. 26(10) · pp. 1636–1643

Diane M. Del Valle✉(Icahn School of Medicine at Mount Sinai)Seunghee Kim‐Schulze(Icahn School of Medicine at Mount Sinai)Hsin-Hui Huang(Icahn School of Medicine at Mount Sinai)Noam D. Beckmann(Icahn School of Medicine at Mount Sinai)Sharon Nirenberg(Icahn School of Medicine at Mount Sinai)Bo Wang(Icahn School of Medicine at Mount Sinai)Yonit Lavin(Icahn School of Medicine at Mount Sinai)Talia H. Swartz(Icahn School of Medicine at Mount Sinai)Deepu Madduri(Icahn School of Medicine at Mount Sinai)Aryeh Stock(Icahn School of Medicine at Mount Sinai)Thomas U. Marron(Icahn School of Medicine at Mount Sinai)Hui Xie(Icahn School of Medicine at Mount Sinai)Manishkumar Patel(Icahn School of Medicine at Mount Sinai)Kevin Tuballes(Icahn School of Medicine at Mount Sinai)Oliver Van Oekelen(Icahn School of Medicine at Mount Sinai)Adeeb Rahman(Icahn School of Medicine at Mount Sinai)Patricia Kovatch(Icahn School of Medicine at Mount Sinai)Judith A. Aberg(Icahn School of Medicine at Mount Sinai)Eric E. Schadt(Icahn School of Medicine at Mount Sinai)Sundar Jagannath(Icahn School of Medicine at Mount Sinai)Madhu Mazumdar(Icahn School of Medicine at Mount Sinai)Alexander W. Charney(Icahn School of Medicine at Mount Sinai)Adolfo Firpo‐Betancourt(Icahn School of Medicine at Mount Sinai)Damodara Rao Mendu(Icahn School of Medicine at Mount Sinai)Jeffrey S. Jhang(Icahn School of Medicine at Mount Sinai)David L. Reich(Icahn School of Medicine at Mount Sinai)Keith Sigel(Icahn School of Medicine at Mount Sinai)Carlos Cordon‐Cardo(Icahn School of Medicine at Mount Sinai)Marc Feldmann(University of Oxford)Samir Parekh(Icahn School of Medicine at Mount Sinai)Miriam Mérad(Icahn School of Medicine at Mount Sinai)Sacha Gnjatic(Tisch Hospital)

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COVID-19 Clinical Research Studies Long-Term Effects of COVID-19 SARS-CoV-2 and COVID-19 ResearchMedicineInternal medicineDiseaseCytokineTumor necrosis factor alphaCohortProspective cohort studySeverity of illnessImmunologyCohort study

MeSH terms

BetacoronavirusCOVID-19SARS-CoV-2AgedFemaleHospitalizationHumansMaleMiddle AgedPneumonia, ViralSeverity of Illness IndexTumor Necrosis Factor-alphaInterleukin-6Survival RateCytokines