article Open AccessTop 1% cited
Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)
American Heart Journal · 2011 · Vol. 162(4) · pp. 597–605
Paul M. Ridker✉(Brigham and Women's Hospital)Tom ThurénAndrew ZalewskiPeter Libby(Harvard University)
Atherosclerosis and Cardiovascular DiseasesInflammasome and immune disordersAdipokines, Inflammation, and Metabolic DiseasesMedicineCanakinumabThrombosisIntensive care medicineInternal medicineAnakinraDisease
MeSH terms
Antibodies, MonoclonalCardiovascular DiseasesHumansMyocardial InfarctionRecurrenceThrombosisStrokeDiabetes ComplicationsAtherosclerosisInterleukin-1betaAntibodies, Monoclonal, Humanized
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References
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
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Journal of the American College of Cardiology · 2009 · 2,133 citations
The immune response in atherosclerosis: a double-edged sword
Nature reviews. Immunology · 2006 · 2,170 citations
Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice
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