articleTop 1% cited
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
Nature Genetics · 2001 · Vol. 27(4) · pp. 383–391
Peter Kuehl✉(University of Maryland, Baltimore)Jiong Zhang(Johns Hopkins Medicine)Yvonne Lin(University of Washington)Jatinder K. Lamba(St. Jude Children's Research Hospital)Mahfoud Assem(St. Jude Children's Research Hospital)John D. Schuetz(St. Jude Children's Research Hospital)Paul B. Watkins(University of North Carolina at Chapel Hill)Ann K. Daly(Newcastle University)Steven Wrighton(Eli Lilly (United States))Stephen D. Hall(Indiana University – Purdue University Indianapolis)P Maurel(Inserm)Mary V. Relling(St. Jude Children's Research Hospital)Cynthia Brimer(St. Jude Children's Research Hospital)Kazuto Yasuda(St. Jude Children's Research Hospital)Raman Venkataramanan(University of Pittsburgh)Stephen C. Strom(University of Pittsburgh)Kenneth E. Thummel(University of Washington)Mark S. Boguski(National Center for Biotechnology Information)Erin G. Schuetz(St. Jude Children's Research Hospital)
Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and ProtectionDrug Transport and Resistance MechanismsBiologyCYP3A5CYP3ASingle-nucleotide polymorphismGeneticsGeneAlternative splicingAlleleRNA splicingMessenger RNA
MeSH terms
AllelesCytochrome P-450 Enzyme SystemHumansMolecular Sequence DataPromoter Regions, GeneticAlternative SplicingPolymorphism, Single NucleotideRacial GroupsCytochrome P-450 CYP3A
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