reviewTop 1% cited
The Bcl2 family: regulators of the cellular life-or-death switch
Nature reviews. Cancer · 2002 · Vol. 2(9) · pp. 647–656
Suzanne Cory✉(Walter and Eliza Hall Institute of Medical Research)Jerry M. Adams(The Royal Melbourne Hospital)
Cell death mechanisms and regulationCancer-related Molecular PathwaysMitochondrial Function and PathologyCaspaseApoptosisProteasesRegulatorCell biologyBcl-2 familyProgrammed cell deathIntracellularIntrinsic apoptosisCancer research
MeSH terms
AnimalsHumansModels, MolecularNeoplasmsProtein ConformationApoptosisProto-Oncogene Proteins c-bcl-2Caspases
Funding
- Leukemia and Lymphoma Society
- National Institutes of Health
- National Health and Medical Research Council
- National Medical Research Council
Citations
3,945
FWCI
64.04
field-weighted impact
References
155
Percentile
100%
vs. same field & year
Citations per year
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References
Mechanisms of Caspase Activation and Inhibition during Apoptosis
Molecular Cell · 2002 · 1,810 citations
PUMA, a Novel Proapoptotic Gene, Is Induced by p53
Molecular Cell · 2001 · 2,283 citations
Life-or-death decisions by the Bcl-2 protein family
Trends in Biochemical Sciences · 2001 · 882 citations
The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues
Molecular Cell · 2000 · 1,468 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
British Journal of Cancer · 1972 · 15,557 citations
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Cell · 1998 · 4,423 citations
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
The EMBO Journal · 1998 · 1,231 citations
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