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Anticancer activities of histone deacetylase inhibitors

Nature Reviews Drug Discovery · 2006 · Vol. 5(9) · pp. 769–784
Jessica E. BoldenMelissa J. PeartRicky W. Johnstone
Histone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsEpigenetics and DNA MethylationEpigeneticsHistone deacetylaseAcetylationHistoneChromatinHDAC11Histone deacetylase 5ChemistryBiologyComputational biology

MeSH terms

Antineoplastic AgentsCell CycleEnzyme InhibitorsHistone DeacetylasesHumansNeoplasmsApoptosisHistone Deacetylase Inhibitors
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References
Histone-deacetylase inhibitors: novel drugs for the treatment of cancer
Nature Reviews Drug Discovery · 2002 · 1,513 citations
Prospects: Histone deacetylase inhibitors
Journal of Cellular Biochemistry · 2005 · 478 citations
HSP90 and the chaperoning of cancer
Nature reviews. Cancer · 2005 · 2,468 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Life in the balance: how BH3-only proteins induce apoptosis
Current Opinion in Cell Biology · 2005 · 740 citations
The Bcl2 family: regulators of the cellular life-or-death switch
Nature reviews. Cancer · 2002 · 3,945 citations
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