review Open AccessTop 1% cited
Autophagy in infection, inflammation and immunity
Nature reviews. Immunology · 2013 · Vol. 13(10) · pp. 722–737
Vojo Deretić✉(University of New Mexico)Tatsuya Saitoh(Osaka International University)Shizuo Akira(Osaka University)
Autophagy in Disease and TherapyExtracellular vesicles in diseaseMicroRNA in disease regulationAutophagyInflammasomeInflammationBiologyCell biologyImmune systemAntigen presentationImmunityInnate immune systemAcquired immune system
MeSH terms
AutophagyBacterial InfectionsGene Expression RegulationHomeostasisHumansImmunity, InnateInflammationT-LymphocytesVirus DiseasesSignal TransductionAntigen PresentationProtein TransportAdaptor Proteins, Signal TransducingReceptors, Pattern RecognitionInflammasomes
Citations
1,849
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81.62
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References
151
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100%
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References
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
Nature Cell Biology · 2013 · 1,512 citations
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Nature Immunology · 2012 · 1,359 citations
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Nature Immunology · 2010 · 2,930 citations
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
The EMBO Journal · 2007 · 2,074 citations
JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
Molecular Cell · 2008 · 1,299 citations
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Nature · 2007 · 9,601 citations
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
The Journal of Cell Biology · 2005 · 3,224 citations
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