reviewTop 1% cited
Activation and regulation of the inflammasomes
Nature reviews. Immunology · 2013 · Vol. 13(6) · pp. 397–411
Eicke Latz✉(University of Bonn)Tsan Sam Xiao(National Institutes of Health)Andrea Stutz(University of Bonn)
Inflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideAdenosine and Purinergic SignalingInflammasomeCell biologyAutophagyAIM2SignallingBiologyNALP3ExtracellularIntracellularImmune system
MeSH terms
NLR Family, Pyrin Domain-Containing 3 ProteinAutophagyCarrier ProteinsHumansSignal TransductionReceptors, Interleukin-1Models, ImmunologicalInflammation MediatorsInterleukin-18Interleukin-1betaInflammasomes
Funding
- National Institute of Allergy and Infectious Diseases
Citations
2,842
FWCI
93.74
field-weighted impact
References
156
Percentile
100%
vs. same field & year
Citations per year
Cited by
NLRP3 inflammasome: Its regulation and involvement in atherosclerosis
Journal of Cellular Physiology · 2017 · 480 citations
<scp>GSDMD</scp> membrane pore formation constitutes the mechanism of pyroptotic cell death
The EMBO Journal · 2016 · 1,131 citations
Microglia: Agents of the CNS Pro-Inflammatory Response
Cells · 2020 · 348 citations
Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors
Cell Death and Disease · 2019 · 1,264 citations
Pyroptosis: A new frontier in cancer
Biomedicine & Pharmacotherapy · 2019 · 1,099 citations
Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
Cell Death and Disease · 2019 · 481 citations
Immunogenic cell death in cancer and infectious disease
Nature reviews. Immunology · 2016 · 2,863 citations
Inflammasomes: mechanism of assembly, regulation and signalling
Nature reviews. Immunology · 2016 · 3,348 citations
References
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
Caspase‐1‐induced pyroptotic cell death
Immunological Reviews · 2011 · 1,135 citations
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
Cell Death and Differentiation · 2007 · 1,418 citations
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
Immunity · 2011 · 3,568 citations
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Immunity · 2012 · 2,103 citations
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Nature Immunology · 2012 · 1,359 citations
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
Cell Death and Differentiation · 2007 · 1,018 citations
Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor
The EMBO Journal · 2006 · 1,427 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.