reviewTop 1% cited
Induction of Apoptosis by Cancer Chemotherapy
Experimental Cell Research · 2000 · Vol. 256(1) · pp. 42–49
Scott H. Kaufmann✉William C. Earnshaw(University of Edinburgh)
Cell death mechanisms and regulationCancer-related Molecular PathwaysPARP inhibition in cancer therapyApoptosisBiologyFas ligandProgrammed cell deathCytochrome cMitochondrionFas receptorReceptorCell biologyIntrinsic apoptosis
MeSH terms
Antineoplastic AgentsCytochrome c GroupHumansMembrane GlycoproteinsMitochondriaNeoplasmsTumor Cells, CulturedApoptosisReceptors, Tumor Necrosis Factorfas ReceptorFas Ligand Protein
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References
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
Annual Review of Biochemistry · 1999 · 2,764 citations
Two CD95 (APO-1/Fas) signaling pathways
The EMBO Journal · 1998 · 2,997 citations
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
The EMBO Journal · 1997 · 1,191 citations
Apoptosis control by death and decoy receptors
Current Opinion in Cell Biology · 1999 · 1,292 citations
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Cell · 1997 · 7,227 citations
BCL-2 family members and the mitochondria in apoptosis
Genes & Development · 1999 · 3,645 citations
Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner
The Journal of Cell Biology · 1999 · 1,926 citations
IAP family proteins---suppressors of apoptosis
Genes & Development · 1999 · 2,549 citations
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