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HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis

Leukemia · 2002 · Vol. 16(4) · pp. 508–519
W. Wei‐Lynn WongJim DimitroulakosMD MindenLinda Z. Penn
Cancer, Lipids, and MetabolismLipoproteins and Cardiovascular HealthMetal complexes synthesis and propertiesMevalonate pathwayFarnesyl pyrophosphateStatinGeranylgeranyl pyrophosphateCancer researchApoptosisHMG-CoA reductaseIn vivoPharmacologyMedicine

MeSH terms

Antineoplastic AgentsCell DivisionHumansNeoplasmsApoptosisHydroxymethylglutaryl-CoA Reductase Inhibitors
Citations
574
FWCI
7.80
field-weighted impact
References
166
Percentile
98%
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Citations per year
References
Induction of Apoptosis by Cancer Chemotherapy
Experimental Cell Research · 2000 · 1,257 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Bcl-2 family proteins
Oncogene · 1998 · 1,055 citations
Apoptosis control by death and decoy receptors
Current Opinion in Cell Biology · 1999 · 1,292 citations
BCL-2 family members and the mitochondria in apoptosis
Genes & Development · 1999 · 3,645 citations
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HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis · Scinovex