article Open AccessTop 1% cited
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
The EMBO Journal · 1997 · Vol. 16(10) · pp. 2794–2804
Jan Paul Medema✉(Heidelberg University)
Immunotherapy and Immune ResponsesUbiquitin and proteasome pathwaysDNA Repair MechanismsGermanLibrary scienceResearch centerArt historyClassicsHistoryMedicinePathologyComputer science
MeSH terms
AnimalsCarrier ProteinsCysteine EndopeptidasesEnzyme ActivationHumansIsoenzymesModels, BiologicalPrecipitin TestsProtein BindingViral ProteinsSignal TransductionSerpinsCysteine Proteinase InhibitorsApoptosisfas Receptor
Funding
- KWF Kankerbestrijding
Citations
1,191
FWCI
39.12
field-weighted impact
References
49
Percentile
100%
vs. same field & year
Citations per year
Cited by
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
Annual Review of Biochemistry · 1999 · 2,764 citations
BCL-2 family members and the mitochondria in apoptosis
Genes & Development · 1999 · 3,645 citations
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) Apoptosis Systems
Experimental Cell Research · 2000 · 625 citations
Induction of Apoptosis by Cancer Chemotherapy
Experimental Cell Research · 2000 · 1,257 citations
Two CD95 (APO-1/Fas) signaling pathways
The EMBO Journal · 1998 · 2,997 citations
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
The EMBO Journal · 1997 · 1,297 citations
Anoikis resistance and tumor metastasis
Cancer Letters · 2008 · 633 citations
The CD95(APO-1/Fas) DISC and beyond
Cell Death and Differentiation · 2003 · 1,064 citations
References
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.
The EMBO Journal · 1995 · 2,138 citations
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
Journal of Immunological Methods · 1991 · 4,625 citations
Analytical Properties of the Nanoelectrospray Ion Source
Analytical Chemistry · 1996 · 1,846 citations
Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels
Analytical Chemistry · 1996 · 9,049 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
