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Targeting Free Radicals in Oxidative Stress-Related Human Diseases

Trends in Pharmacological Sciences · 2017 · Vol. 38(7) · pp. 592–607
Patrik PopracKlaudia JomováMiriama ŠimunkováVojtech KollárChristopher J. RhodesMarián Valko
Free Radicals and AntioxidantsRedox biology and oxidative stressCholinesterase and Neurodegenerative DiseasesOxidative stressReactive oxygen speciesThioredoxinAntioxidantGlutathioneSuperoxide dismutaseNeuroprotectionChemistryPharmacologyBiochemistry

MeSH terms

Alzheimer DiseaseAntioxidantsChelating AgentsFree RadicalsHumansNeoplasmsFree Radical ScavengersReactive Oxygen SpeciesOxidative Stress

Funding

  • European Commission
  • Vedecká Grantová Agentúra MŠVVaŠ SR a SAV
Citations
1,086
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References
FDA-approved small-molecule kinase inhibitors
Trends in Pharmacological Sciences · 2015 · 991 citations
Cholinesterase inhibitors for Alzheimer's disease
Cochrane Database of Systematic Reviews · 2006 · 1,851 citations
Modulation of oxidative stress as an anticancer strategy
Nature Reviews Drug Discovery · 2013 · 3,495 citations
Induction of Apoptosis by Cancer Chemotherapy
Experimental Cell Research · 2000 · 1,257 citations
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Nature Reviews Drug Discovery · 2009 · 5,229 citations
Free radicals and antioxidants – quo vadis?
Trends in Pharmacological Sciences · 2011 · 696 citations
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